An Assessment of In Ovo Toxicity of the Flame Retardant 1,2-Dibromo-4-(1,2-Dibromoethyl) Cyclohexane (TBECH) in the Zebra Finch
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| Authors: | Currier, HA; Letcher, RJ; Williams, TD; Elliott, JE |
| Year: | 2013 |
| Journal: | Bulletin of Environmental Contamination and Toxicology 91: 455-459 Article Link (DOI) |
| Title: | An Assessment of In Ovo Toxicity of the Flame Retardant 1,2-Dibromo-4-(1,2-Dibromoethyl) Cyclohexane (TBECH) in the Zebra Finch |
| Abstract: | Embryonic toxicity of a brominated flame retardant, TBECH (1,2-dibromo-4-(1, 2-dibromoethyl) cyclohexane) was investigated using the zebra finch (Taeniopygia guttata) as our model. Using in ovo dosing procedures, we injected the technical TBECH compound, consisting of 50:50 alpha-/beta-isomers, directly into the yolk of freshly laid eggs at concentrations of 2.3-94 ng/g egg. No significant effects were observed in terms of growth or survival for either pre-hatch embryos or post-hatch chicks. Analysis of tissue samples at various developmental stages suggests that alpha-/beta-TBECH was metabolized rapidly, and thus is unlikely to cause any direct, long-term effects on the development of zebra finch embryos or offspring. |
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