|Neutralizing antibodies to seasonal coronaviruses and their correlation to SARS-CoV-2 neutralizing antibodies
The Pantophlet Lab is seeking highly self-motivated BISC 498/499 students for Summer 2021 and Fall 2021 to participate in COVID-19 related lab research. Interested students must have an excellent academic record and completed (B+ or higher) at least one, but preferably two or more, upper-division laboratory courses in biochemistry, microbiology, immunology, virology, or molecular biology. Interested students also must have excellent organizational and time management skills and be able to dedicate at least 12 hours per week due the envisioned project. Students with previous work experience in a biomedical research lab (e.g., through co-op), especially if interested in pursuing graduate studies in biomedical sciences, are particularly encouraged to send an email directly to Dr. Ralph Pantophlet (email@example.com). The email must include a brief statement of intent (<250 words), a current academic transcript and a CV detailing lab skills plus any notable academic and non-academic achievements. All applicants will be reviewed based on merit, but preference will be given to those who identify as BIPOC or 2SLGBTQ+ in cases of equal merit.
Summer SEMESTER 2021 (498/499/497 students)
I am looking for 6-8 students to work collaboratively on a project aimed at the gamification of or design of a game for the Bisc 202 course (Intro genetics). The project will be divided into several sections that will somewhat vary depending on the skills and interests students bring to the project. We will begin with a literature search on the topic of the use of games in education and the production of an annotated bibliography, followed by the development of a set of best practices in game use/gamification. You will then design a game or gamification strategy for intro genetics, describing the format the game should take, which learning outcomes are best suited for this purpose, how mastery of the outcomes can be rewarded in the game, and how achievement in the game can be connected to course credit (or not). There is a variety of models or forms this can take - you may work in teams or on your own. You will present your work in written form, but will also make an oral presentation if you wish.
Skills you will develop or improve:
Reading the pedagogical literature
Personal management, organization, meeting deadlines etc.
Collaborative writing of rationale, report, and/or proposal
Oral presentation skills (if you wish; most of our recent grads say they didn't have enough chances to develop oral communication skills during their undergrad)
Note that these courses don't result in an automatic A. But you'll have lots of feedback and practice that should lead to you improving greatly, especially in writing, so that you can produce work you are proud of.
Not a straight A student?
Who cares? I am looking for a variety of students, who are looking to develop skills and use some creativity. The more diverse our group, the better it will be. If you are enthusiastic, hardworking, reliable and willing to explore some unknown territory, that is good enough for me.
Also, please note that this project does not count as a lab course. And I cannot run it as designed without a large enouch group. I need at least 6 participants!
|Evolutionary biology of human health and disease|
We determine the roles of trade-offs, genomic conflicts, and Darwinian natural selection in the evolution of human psychological and physiological adaptations and disease risks.
We are currently focusing especially on autism, schizophrenia, endometriosis, and polycystic ovary syndrome. Research on other topics of interest is also a possibility.
See my google scholar page for recent publications.
|How do organisms obtain information about foraging payoffs in their environment?|
Foraging animals constantly make decisions about whether to stay where they are or move to a new foraging patch. Animals should forage in patches where they can get the highest payoff, but how do they gain information about the payoffs available in their environment? To explore this question, we are seeking a 298/498 student to undertake experiments on the foraging decisions of wild Steller’s jays feeding on peanuts in trays.
|Ron Ydenberg, Tom Flower|
|Competition between ravens and crows in Metro Vancouver|
Ravens have become a common site in Metro Vancouver, but little is known about how they affect the urban environment. Observations suggest that ravens compete with crows for resources and ravens have even been observed predating crow eggs and chicks. The presence of ravens may therefore have important consequences for crow distribution and behaviour, with further consequences for crow prey species.
We are looking for a student or students to undertake a BISC498 project investigating the distribution of breeding raven pairs within Metro Vancouver and the consequences for crow distribution and nesting success in proximity to raven breeding territories. Additionally, we would seek to obtain some simple information on crow foraging behaviour within the city, specifically what proportion of their diet they gain from eating European chafer beetles. Together this work explores intraguild competition between predatory species and the potential consequences for interactions across trophic levels.
|Ron Ydenberg, Tom Flower|
|Drinking water stagnation and water quality|
Water stagnation in building plumbing results in deterioration of water quality. Common hazards caused by water stagnation include the growth of microbes including pathogenic species such as Legionella spp., and elevated metal levels, including lead and copper. The reduced occupancy of numerous workplaces during the COVID-19 pandemic has highlighted this issue. We are looking for research project students (49X or ISS) who are interesting in contributing to a project on assessing the impacts of long-term drinking water stagnation, and methods for remediating it. This will involve collecting water samples and performing water quality tests, as well as reviewing the relevant literature.
|Stable fly host seeking and mate recognition Need Volunteer|
Looking for students interested in visual communication//host-seeking behaviours//entomology or all of the above! My research focuses on determining the visual mate recognition and host-seeking cues used by a blood-feeding parasite of cattle (Stomoxys calcitrans). Duties primarily consist of video analysis of laboratory and field experiments. Time commitment and work schedule is highly flexible. Opportunities are currently limited to remote work. If interested (or if you have any questions) please feel free to send me an email!
|Western tent caterpillar ecology|
We are looking for a student for Summer 2020 to be involved in field sampling the western tent caterpillar and also other experiments in the lab with the cabbage looper. We are particularly interested in how disease affects insect dynamics and how pathogens interact with both host plant and the microbiota around them. Ideally the student would apply for an NSERC USRA (deadline around mid January 2020) - which I can help you prepare. Students interested in other projects such as ISS or 49X and also volunteers are also welcome. Please contact me for further information.
This project is available for students who are interested in taking on an undergraduate research project (BISC 498 or BISC 499) under the pedagogical research category.
I am looking for 4-6 students to work collaboratively on a project aimed at the gamification of a BISC course. The project will be divided into several sections that will somewhat vary depending on the skills and interests students bring to the project. We will begin with a literature search on the topic of the use of games in education, followed by a rationale (benefits/drawbacks) for using a game platform in a course. We will then select Bisc 202 or Bisc 333 and determine what format the game should take, which learning outcomes are best suited for this purpose, how mastery of the outcomes can be rewarded in the game, and how achievement in the game can be connected to course credit. There is a variety of models or forms this can take - we will examine several and collaboratively select one. We will work on outlining the steps needed to develop the game and will finish up with a proposal and/or storyboards, again depending on the skills and interests of project participants, and the direction the group wants to take.
Skills you will develop or improve:
Reading the pedagogical literature
Personal management, organization, meeting deadlines etc.
Collaborative writing of rational, report, and/or proposal
Not a straight A student?
Who cares? I am looking for a variety of students, who are looking to develop skills and use some creativity. If you are enthusiastic, hardworking, reliable and willing to explore some unknown territory, that is good enough for me.
|Factors influencing maternal investment during mammalian pregnancy|
Prenatal development determines health throughout life, and the placenta plays a critical role in supplying the fetus with nutrients and oxygen. Carefully regulated interactions between the placenta and the lining of the mother’s uterus are crucial to normal placental development and a healthy pregnancy. I am interested in both the molecular basis and the evolution of these interactions. In a related project, I am studying the effects of pregnancy and lactation on the maternal skeleton. Research opportunities are available in my lab involving a variety of molecular techniques, as well as analyses of publicly-available data.
|Spider rearing Need Volunteer|
We rear spiderlings (Steatoda grossa) to adulthood. Workload would be ~1-4h/week (you can choose). Worktimes are highly flexible as work has to be done 1x/week (any day, any time, can vary from week to week - to your convinience). Spiders are fed with Drosophila or Blowflies. If you are interested, please feel free to meet up with me, and after an intro session you can decide if you want to commit.
Don't hesitate to shoot an email if you are interested!
|Interspecies Pheromone Communication Need Volunteer|
Looking for someone who is interested in pheromone communication across species. Opportunity for independent research experience with as much guidance as you like. Field research is underway testing small mammal response to our candidate pheromones. Current sites are in Langley with more on the way all around the SFU Burnaby campus. There is a laboratory bioassay component as well if a student is interested and driven! Both field and laboratory research make for a well-rounded experience. One experiment is focused on testing cats' response, possibly making a new cat toy, although opportunities here are limited.
If you’re a third or fourth year biology undergraduate at Simon Fraser University and want some hands-on conservation experience, think about applying to the internship program on Haida Gwaii. You could obtain the opportunity for a field studies internship with the Laskeek Bay Conservancy Society on Haida Gwaii. After a week with their office in Queen Charlotte, you’ll live for a month on East Limestone Island in Laskeek Bay and help with field work, such as avian and marine mammal surveys, and maintenance work such as pulling invasive species and doing beach cleanups. You’ll be a member of an enthusiastic team, gain new skills, and spend time in a beautiful environment with seabirds and other local creatures.
You may also be able gain some academic credit by using some of your field time to complete an undergraduate research course, working with Prof. Ron Ydenberg.
If this experience sounds good to you, visit the Laskeek Bay Conservancy Society website for details http://www.laskeekbay.org. At SFU you can contact the Biology undergrad advisor Emelia Kirkwood (Emelia_kirkwood@sfu.ca), or Ron Ydenberg (firstname.lastname@example.org).
|Birds, bats and beetles: investigating the role of habitat, prey availability and competition on the bat community in Ontario|
Are you interested in animal ecology and conservation?
We are looking for an undergraduate student interested in pursuing an ISS (Honours) project investigating interactions between bats and a bird, the whip-poor-will, within a nocturnal aerial insectivore community facing a variety of conservation threats.
Project requires analysis of ultrasonic and acoustic recordings, basic statistics and good writing skills.
|Philina English & David Green|
|Macroevolution and Conservation|
Our lab is busy applying phylogenetics to conservation, particularly in the context of the EDGE program administered out of the London Zoo. So, we are building phylogenetic trees, looking for data on conservation status, and also looking at how ecologically-interesting traits evolve on those trees. If you are interested and know lots about a taxonomic group, or want to learn, let us know.
|Vision in aquatic animals|
Vision is of fundamental importance in the lives of many animals. We are interested in cellular specializations and physiological mechanisms that determine the ability of animals to detect and process the colour and polarization of light, as well as the ecological functions of such visual capabilities in nature. Our research ranges from identifying cellular mechanisms that control visual pigment protein (opsin) expression in photoreceptors of the vertebrate retina to ecological investigations of ultraviolet and polarization sensitivity in aquatic animals. A variety of research projects are available for Bisc 498 or ISS projects, or for graduate studies (specially if you can obtain a major graduate fellowship, e.g., from NSERC or CIHR).
|Inigo Novales Flamarique|
|Photo taxis/tropism in plants and slime molds.|
Both plant and slime molds (Dictyostelium discoideum) exhibit positive phototropism or phototaxis. In plants it’s the tip that grows by elongation and cell division and in the slime molds it is the multicellular slug that towards the light source. Individual cells in these species do not orient and move (elongate) towards the light, rather it is the combined interaction of many semi-attached cells that leads to this bending towards the light. The mechanism responsible is that cells that are further away from the light source move/elongate faster than the cells that are closer. Since the cells are attached to each other the result is a bending of the tip or the front of the slug. When the tip points towards the light, both sides sense the same light intensity, the differential movement halts, and the tip/slug moves straight forward. In our lab we want to explore the similarities between Dictyostelium phototaxis and Arabidopsis phototropism. Are there common genes involved. The project will involve, growing Dictyostelium cells and Arabidopsis plants and then taking time laps movies of slug movements and tip bending under directional light. We then will compare the results with results for mutants in phototaxis or phototrophism.
This project is in collaboration with Sherryl Bisgrove email: email@example.com
|Immune responses in vectors|
Insects transmit parasites to humans that cause significant diseases. Some diseases cause significant mortality (malaria kills 2-3 million people/year). Our research addresses how these vectors recognize and kill these parasites, or allow them to develop and get transmitted. This included recognizing the parasite as non-self and then turning on aspects if its immune responses. Projects are available to identify immune genes, express proteins, kill parasites or pathogens, all while working with a great fun loving bunch of researchers!
|Examining mitochondrial dynamics in healthy cells and in human disease processes.|
Mitochondria are usually described as the "powerhouses" of cells, however they also play other pivotal roles in the life and death processes of eukaryotic cells. They display great variation in number, shape and location inside different cell types, appearing as large reticular networks in some cells and as small, punctate, autonomous organelles in others. Mitochondria are also highly dynamic organelles, they can undergo fission, fusion and can be rapidly transported around cells. In my lab we study the mechanisms of these processes in living cells. In addition we study the role of "mitochondrial dynamics" in disease processes, particularly in neurodegenerative disorders such as Parkinson's Disease and Stroke. Student projects are available in my lab to study the basic mechanisms of regulating mitochondria dynamics, and to examine how changes in mitochondrial dynamics are involved in neurodegenerative diseases. Students in my lab will employ techniques including molecular biology (amplification and purification of DNA vectors, construction of mammalian expression vectors), cell culture (tissue culture techniques for various cell types, aseptic technique, transfection of astrocytes/neurons with expression vectors) and fluorescence microscopy (live-cell image acquisition, real-time perfusion experiments, image analysis).
|Axon guidance in C. elegans|
Neuronal circuits are the fundamental functional units in the brain. They are established during embryonic development. One central aspect of neuronal circuit formation is the directed outgrowth of neuronal processes (axons and dendrites). They have to navigate precisely towards their target areas where they establish synaptic connections with target cells to eventually form neuronal circuits. Our lab studies the genetic and molecular basis of this navigation process using C. elegans as a model organism.
Projects for undergraduate students in my lab revolve around this topic as well. You will get a chance to learn to work with C. elegans, one of the major genetic model organisms. You will learn genetic, molecular biology and microscopic techniques.
Current projects include:
- Generation of mutants in selected genes with a suspected role in axon guidance
- RNAi screens to identify novel genes with a potential role in axon guidance
- Characterization of existing mutants for potential axon guidance phenotypes
- Mapping of mutations isolated in genetic screens